Publications by authors named "T van Lith"
Objectives: SARS-CoV-2 infection is associated with a decline in functional outcomes; many patients experience persistent symptoms, while the underlying pathophysiology remains unclear. This study investigated white matter (WM) integrity on brain MRI in hospitalized COVID-19 patients and its associations with clinical outcomes, including long COVID.
Materials And Methods: We included hospitalized COVID-19 patients and controls from CORONavirus and Ischemic Stroke (CORONIS), an observational cohort study, who underwent MRI-DWI imaging at baseline shortly after discharge (<3 months after positive PCR) and 3 months after baseline scanning.
Article Synopsis
- This study aimed to evaluate the prevalence of cerebrovascular MRI markers in patients hospitalized for COVID-19 compared to healthy controls without prior COVID-19 infection or hospitalization.
- Conducted as an observational cohort study, it involved brain MRIs done shortly after discharge and again after three months, focusing on various cerebrovascular issues.
- The results showed no significant difference in cerebrovascular MRI markers between COVID-19 patients and controls, with only a small percentage experiencing new cerebrovascular lesions after three months, suggesting limited impact of COVID-19 on these markers.
Introduction: Patent foramen ovale (PFO) closure prevents recurrent ischemic stroke in selected patients with a cryptogenic stroke. Trial results tend to be generalized to daily practice, often extending original trial inclusion criteria. This may result in unnecessary closure without benefit, but with risk of complications.
View Article and Find Full Text PDFThis collection focuses on creative art therapies, practices, and interventions in health contexts as part of the Mind-body interventions series of BMC Complementary Medicine and Therapies. The collection highlights the emerging value of the arts in complementary medicine and contributes to the expanding knowledge and integration of mind-body interventions and creative art practices.
View Article and Find Full Text PDFIn coronavirus disease 2019 (COVID-19), endothelial cells play a central role and an inadequate response is associated with vascular complications. PET imaging with gallium-68 labelled RGD-peptide (Ga-RGD) targets αβ integrin expression which allows quantification of endothelial activation. In this single-center, prospective observational study, we included ten hospitalized patients with COVID-19 between October 2020 and January 2021.
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