Publications by authors named "T de Backer"

Communication professionals in Federal agencies must have a seat at their agency's budget formulation table - to inform the budget process from the beginning and to advise on funding for the communications required to achieve program goals. This is one of nine lessons learned from US Department of Health and Human Services (USDHHS) systems change efforts that were applied to help create the "We Can Do This" COVID-19 Public Education Media Campaign (Campaign), and these lessons were presented in a 2022 article. Now that substantial evaluation data are available in eight recent research articles to verify the Campaign's success, this lesson can be revisited to identify more specific ways in which it can be applied, along with two additional lessons identified from the Campaign implementation.

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Article Synopsis
  • The study investigates how renal artery stenosis (RAS) affects blood flow and renin release in a pig model, particularly when there is significant stenosis on the opposite kidney side.
  • Researchers measured kidney pressure and blood flow while gradually blocking the renal artery to understand how these changes impact renin secretion.
  • Findings revealed that a 25% reduction in renal perfusion pressure significantly reduced blood flow and increased renin release, especially when there was already significant stenosis in the contralateral kidney.
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Aims: To examine the association of daily PA levels and sedentary behaviour with body composition, estimated insulin sensitivity, and arterial stiffness in adults with type 1 diabetes (T1D).

Methods: Cross-sectional study in adults with T1D (n = 54). PA levels (daily steps, and time in moderate-to-vigorous intensity PA (MVPA)) and sedentary behaviour were measured using accelerometry for 7 days (McRoberts® DynaPort MoveMonitor).

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Arterial hypertension is a major risk factor for cardiovascular morbidity and mortality, and highly prevalent in older age, underscoring the importance of its appropriate management. The population is ageing at an increasing rate, with those aged 80+ years being the fastest growing population characterized by high heterogeneity in terms of functionality and autonomy. The prevalence of hypertension rises with increasing age, due to a significant increase in SBP largely as a result of age-related stiffening of the aorta and other large arteries, affecting almost 80% of those aged 80+ years.

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Aims: The management of patients treated with direct oral anticoagulants (DOACs) during hospitalization is a common challenge in clinical practice. Although bridging is generally not recommended, too often DOACs are switched to parenteral therapy with low molecular weight heparins. Our objectives were to update a local guideline for perioperative DOAC management and to develop a guideline for the anticoagulation management in non-surgical patients regarding temporary DOAC discontinuation.

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