A combination of gold nanoparticles and laser photobiomodulation to boost antioxidant defenses in the recovery of muscle injuries caused by Bothrops jararaca venom.

Unlabelled: This study aimed to evaluate gold nanoparticles (GNPs) and photobiomodulation (PBM), associated with antibothropic serum (AS), to treat a muscle lesion induced by Bothrops jararaca venom.

Methods: 108 Swiss male mice were used, divided into nine groups (n = 12) with different combinations of treatments. Animals were inoculated with 250 µg of B.

Feasibility of embedding orthopaedic clinical trials into national registries: a pilot quality improvement study for the UK Non-Arthroplasty Hip Registry (UK-NAHR).

The integration of 'Registry-based Randomised Control Trials' (RRCT) into national registries has the potential to catalyse prospective research, enhancing the evidence base for practice. The aim of this study was to assess the feasibility of embedding a trial within the UK Non-Arthroplasty Hip Registry. This was a national observational, multi-centre study.

Is physical exercise effective in improving pain, functional mobility and quality of life in individuals with hip osteoarthritis? A systematic review with meta-analysis.

Objective: To evaluate the effectiveness of physical exercise and its implications on pain, functional mobility (FM) and quality of life (QoL) in individuals with isolated hip osteoarthritis (HO).

Design: Intervention systematic review.

Literature Search: Pubmed, Embase, CINAHL, CENTRAL (Cochrane) and PEDro were searched for studies evaluating the effect of exercise on pain, FM and QoL in people with HO from the first publication until August 2022.

Evidence of Clinical and Laboratory Correlation of Itraconazole Resistance in Infection: Case Report.

Sporotrichosis is a subcutaneous infection caused by fungi from the genus , among which displays high virulence and transmissibility. So far, classical antifungal agents have been efficient against , but here we describe the first case of therapeutic failure and a high minimum inhibitory concentration (MIC) in relation to itraconazole.