Publications by authors named "T Zingoni"

Background/objectives: Many lasers applied in skin rejuvenation protocols show emissions with wavelengths falling in the red or near-infrared (NIR) bands. To obtain further in vitro data on the potential therapeutic benefits regarding rejuvenation, we employed a 675 nm laser wavelength on cultured human dermal fibroblasts to understand the mechanisms involved in the skin rejuvenation process's signaling pathways by analyzing cytoskeletal proteins, extracellular matrix (ECM) components, and membrane integrins.

Methods: Normal human dermal fibroblasts (NHDFs) were irradiated with a 675 nm laser 24 h after seeding, and immunofluorescence microscopy and Western blotting were applied.

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The purpose of this clinical case was to test the efficacy and safety of the long-pulsed 1064-nm neodymium-YAG laser in the treatment of multiple angiokeratomas on the labia majora of the vulva. Benign vascular neoplasms known as angiokeratomas are characterized by well-defined, hyperkeratotic, reddish-black papules, or plaques. The patient underwent one treatment session with a long-pulsed 1064-nm neodymium-YAG laser.

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Acne vulgaris is a persistent inflammatory condition affecting the sebaceous unit, in whose pathophysiology the Propionibacterium acnes (P. acnes) play an important role, and that can have major psychological effects. The current study aims to investigate the safety and efficacy of an innovative fractional microneedle radiofrequency (RFMN) device for acne management in adolescents.

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: Urinary incontinence (UI) is the involuntary loss of urine caused by a weakness in the pelvic floor muscles (PFMs) that affects urethral closure. Myostatin, which prevents the growth of muscles, is a protein expressed by human skeletal muscle cells. Indeed, it has been observed that myostatin concentration rises during skeletal muscle inactivity and that suppressing serum myostatin promotes muscle growth and strength.

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