Publications by authors named "T Zagoni"

Introduction And Objectives: coeliac disease (CD) and its cutaneous manifestation, dermatitis herpetiformis are both (DH) gluten-sensitive diseases. Metabolic bone disease is common among patients with CD, even in asymptomatic forms. Data are scarce about bone density in patients with dermatitis herpetiformis.

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Unlabelled: Coeliac disease (gluten-sensitive enteropathy, sprue) is a chrocic disorder of the small bowel leading to malabsorption.

Aims: charts of all patients with coeliac disease treated at the 2nd Department of Medicine, Semmelweis University were evaluated.

Patients And Methods: The authors retrospectively analysed the results of a total of 132 patients with coeliac disease (107 females and 25 males; mean age, 37 years; median, 35 years; range, 19-78 years) attending the centre between 1999 and 2010.

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A molecular diagnostic assay using easily accessible peripheral blood would greatly assist in the screening and diagnosis of ulcerative colitis (UC) and Crohn's disease (CD). Transcriptional profiles in blood/biopsy samples from 12 UC (6/12), 9 CD (5/9), 6 non-inflammatory bowel disease (non-IBD) colitis (6/0), and 11 healthy (11/11) patients were assessed by Affymetrix HGU133Plus2.0 microarrays.

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Article Synopsis
  • The study examines how chronic ulcerative colitis (UC) may increase the risk of colorectal cancer by analyzing changes in certain cellular pathways related to inflammation.
  • Researchers assessed the expression of key proteins involved in tissue regeneration and aging in samples from patients with varying levels of active UC and compared them to normal colonic tissue.
  • Findings indicate that in mild inflammation, there is an increase in certain protein expressions, while in severe cases, these expressions decrease, possibly allowing damaged epithelial cells to survive and multiply, which could lead to cancer development.
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