Publications by authors named "T Yuri"
Background: Apolipoprotein E (APOE) ε4 is a significant genetic risk factor for late-onset Alzheimer's Disease and appears to be closely related with brain amyloidosis. Current identification methods for APOE ε4 carriers are mostly based on genotyping which cannot always predict the specific ApoE protein isoform. We present a case study of a sample with a discordant result for genotype compared to the protein isoform (proteotype) and we reflect on possible implications for future applications.
View Article and Find Full Text PDFObjectives: To investigate the effect of preoperative muscle quality on functional outcomes after total hip arthroplasty (THA).
Design: Retrospective cohort study.
Setting And Participants: We included 426 patients who underwent primary THA between 2015 and 2022 to evaluate the relationship between preoperative muscle quality and 1-year functional outcomes following THA.
Article Synopsis
- - The study investigated the behavioral and psychological symptoms of dementia (BPSD) in patients with Alzheimer’s disease dementia (ADD) and mild cognitive impairment (MCI), focusing on how caregiver relationships affect these symptoms.
- - Researchers evaluated cognitive function in 419 patients using two tests and found significant connections between caregiver relationships and factors like patient age, education level, and total BPSD scores based on the Neuropsychiatric Inventory Questionnaire (NPI-Q).
- - Specific symptoms such as delusions and irritability were notably tied to the caregiver’s relationship with the patient, with female caregivers reporting higher scores in certain emotional symptoms, indicating that the caregiver’s role can influence the patient’s psychological state.
Article Synopsis
- The study investigated how physical activity (PA) relates to muscle quantity and quality in the ankle plantar flexor muscles of patients with knee osteoarthritis (OA).
- A cohort of 92 knee OA patients was examined for PA, leg muscle size, knee strength, and pain, using advanced imaging and regression analyses.
- Findings showed that greater PA was linked to increased normal-density muscle size in the ankle, better knee strength, and less knee pain, highlighting the importance of muscle quality in knee OA patients' activity levels.
Article Synopsis
- The study investigates the ability of remaining rotator cuff (RC) muscles to compensate for humeral head translation in different stages of RC tears, specifically focusing on large tears.
- Using a model with various degrees of RC damage, researchers tested the impact of loading remaining muscles on the translation of the humeral head in cadaveric shoulders.
- Results showed that while some muscle compensations reduced superior translation of the humeral head in moderate tears, significant translation issues persisted in more severe tears, indicating limitations in compensatory mechanisms.