Publications by authors named "T Yu Mayor"

Background: Migrant construction workers involved in building infrastructure for mega-sporting events face elevated risks of illness and death. However, specific health outcomes for these workers have not been systematically reviewed, limiting opportunities to identify and address their challenges.

Methods: This study systematically reviewed health outcomes among migrant construction workers involved in mega-sporting events.

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Article Synopsis
  • * A study using a human mutation library identified certain unstable mutations that predominantly rely on the ubiquitin proteasome system for degradation and found that the co-chaperones DNAJA1 and DNAJA2 interact significantly with one of the mutated proteins.
  • * DNAJA2 plays a dual role: it stabilizes various normal proteins and specifically helps reduce the breakdown of some mutated proteins, highlighting how the protein quality control mechanisms adapt to handle misfolded proteins in the cytosol.
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In this issue of Molecular Cell, Chang et al. elaborate on the mechanisms by which CAT tail aggregation is mediated through threonine residues and how it contributes to the perturbation of proteostasis.

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The initial delivery of small-scale magnetic devices such as microrobots is a key, but often overlooked, aspect for their use in clinical applications. The deployment of these devices within the dynamic environment of the human body presents significant challenges due to their dispersion caused by circulatory flows. Here, a method is introduced to effectively deliver a swarm of magnetic nanoparticles in fluidic flows.

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Ancient lakes are hotspots of species diversity, posing challenges and opportunities for exploration of the dynamics of endemic diversification. Lake Baikal in Siberia, the oldest lake in the world, hosts a particularly rich crustacean fauna, including the largest known species flock of harpacticoid copepods with some 70 species. Here, we focused on exploring the diversity and evolution within a single nominal species, Sars, 1908, using molecular markers (mitochondrial COI, nuclear ITS1 and 28S rRNA) and a set of qualitative and quantitative morphological traits.

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