Publications by authors named "T Yu Magarlamov"

Article Synopsis
  • First-time detection of TTX and 11 related toxins in Cephalothrix mokievskii using advanced HPLC-MS/MS technology.
  • Notable differences in the TTX toxin profiles were found between Cephalothrix mokievskii and its similar species, Cephalothrix cf. simula.
  • The study highlights the geographical distribution of TTX-containing nemerteans and discusses potential impacts on marine ecosystems.
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Article Synopsis
  • Nemerteans, also known as ribbon worms, contain tetrodotoxin (TTXs) and its analogues, which are neurotoxins likely used for hunting and protection.
  • The study analyzed two closely related nemertean species to investigate the distribution and concentration of TTXs in different body parts using advanced techniques like HPLC-MS/MS and fluorescence microscopy.
  • Six types of TTXs-positive cells were identified across both species, with differing concentrations of toxins in various body regions, highlighting unique physiological functions of newly discovered glandular cell types in the intestine.
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Tetrodotoxin (TTX), an extremely potent low-molecular-weight neurotoxin, is widespread among marine animals including ribbon worms (Nemertea). Previously, studies on the highly toxic palaeonemertean cf. showed that toxin-positive structures are present all over its body and are mainly associated with glandular cells and epithelial tissues.

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The toxic ribbon worm, Cephalothrix cf. simula (Palaeonemertea, Nemertea), possesses extremely high concentrations of tetrodotoxin (TTX). Although TTX has been found in the eggs of this species, the fate of the toxin in the ontogeny of the animal has not been explored.

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Bivalves, such as are used as indicator organisms to monitor the state of the marine environment. Even though hemocytes are known to play a key role in the adaptive and protective mechanisms of bivalves, these cells are poorly studied in horse-mussel . In this paper, we present classification of horse-mussel hemocytes based on their immune functions, including the production of specific immune-related molecules, as well as their morphological composition after isolation by density gradient centrifugation.

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