Publications by authors named "T Yonemoto"
The genome sequences of thousands of bacteriophages have been determined and functions for many of the encoded genes have been assigned based on homology to characterized sequences. However, functions have not been assigned to more than two-thirds of the identified phage genes as they have no recognizable sequence features. Recent genome-wide overexpression screens have begun to identify bacteriophage genes that encode proteins that reduce or inhibit bacterial growth.
View Article and Find Full Text PDFAngiosarcoma (AS) is a malignant vascular neoplasm comprising neoplastic endothelial cells accounting for 1%-4% of soft tissue sarcomas. While lymphedema-associated and post-irradiation ASs are almost always driven by a high-level amplification of MYC (8q24), sporadic ASs, including those of breast parenchymal origin, typically lack MYC amplification. Here, we report a case of sporadic breast MYC-amplified AS in a 19-year-old female with no history of lymphedema or irradiation, who was referred to our hospital for an enlarging right breast mass.
View Article and Find Full Text PDFArticle Synopsis
- * It aims to determine if having surgery followed by three courses of adjuvant chemotherapy is as effective as the standard approach of chemotherapy followed by surgery and then more chemotherapy.
- * The trial is a large, randomized phase III study that began in November 2022 and seeks to confirm that the new treatment method is not inferior regarding overall survival rates.
Article Synopsis
- This study analyzes the long-term postoperative outcomes of limb-sparing surgery in children with knee-borne bone sarcoma, focusing on complications and functional results post-surgery.
- The review included 40 patients under 14 years old and assessed factors like complications, reconstruction success rates, and leg-length discrepancies over a minimum of five years.
- Key findings indicate that younger age and complications negatively affect functional outcomes, with leg-length discrepancies worsening performance, especially in younger patients.*
Objective: The objective of this study was to provide a convenient preoperative prediction of the risk of early postoperative mortality.
Materials And Methods: This retrospective study included patients who underwent surgery for spinal metastasis at our hospital between 2009 and 2021. Preoperative blood test data of all patients were collected, and the survival time was calculated by dividing the blood data.