Publications by authors named "T Yamamori"
Article Synopsis
- Transcranial direct current stimulation (tDCS) shows promise for improving cognitive functions and treating cognitive disorders, but variable outcomes raise concerns about its safety and effectiveness due to unclear neural mechanisms.
- The study investigates tDCS effects on macaque monkeys' cognitive abilities and neuron activity, revealing that tDCS reduced practice-related response slowdowns and altered neuron firing patterns compared to sham stimulation.
- After tDCS, changes in behavior and neuron activity were observed to persist, indicating potential lasting effects, but tDCS did not significantly alter baseline neuron firing rates across multiple applications.
Article Synopsis
- Sensorimotor learning involves changes in neuronal activity in the premotor (PM) and primary motor cortex (M1) of primates, as studied through calcium imaging in common marmosets during a reaching task.
- During the learning process, the dorsorostral PM demonstrated earlier peak activity compared to the dorsocaudal PM and M1, with increased reaction times in pull trials closely correlating with PMdr activity.
- The dorsocaudal PM and M1 maintained stable representation of movements, while PMdc neurons adjusted their preferred movement direction based on push trial performance, highlighting the transition from dynamic tuning in PMdc to stable motor representation in M1 during learning.
The analysis of cells frozen within the International Space Station (ISS) will provide crucial insights into the impact of the space environment on cellular functions and properties. The objective of this study was to develop a method for cryopreserving blood cells under the specific constraints of the ISS. In a ground experiment, mouse blood was directly mixed with a cryoprotectant and gradually frozen at -80 °C.
View Article and Find Full Text PDFMost reports on duplicate dentures are introduction to fabrication methods or clinical case reports. Only a few studies have verified their clinical effectiveness; hence, evidence to construct useful clinical guidelines for duplicate denture use is lacking. This review aimed to comprehensively investigate reports on duplicate dentures to accumulate evidences that will contribute to the formulation of clinical practice guidelines.
View Article and Find Full Text PDFAlterations in the experience-dependent and autonomous elaboration of neural circuits are assumed to underlie autism spectrum disorder (ASD), though it is unclear what synaptic traits are responsible. Here, utilizing a valproic acid-induced ASD marmoset model, which shares common molecular features with idiopathic ASD, we investigate changes in the structural dynamics of tuft dendrites of upper-layer pyramidal neurons and adjacent axons in the dorsomedial prefrontal cortex through two-photon microscopy. In model marmosets, dendritic spine turnover is upregulated, and spines are generated in clusters and survived more often than in control marmosets.
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