Recent advancements in mass spectrometry-based proteomics have made it possible to conduct comprehensive protein analysis. In particular, the emergence of the data-independent acquisition (DIA) method powered by machine learning has significantly improved protein identification efficiency. However, compared with the conventional data-dependent acquisition (DDA) method, the degree to which peptides are uniquely identified by DIA and DDA has not been thoroughly examined.
View Article and Find Full Text PDFPlasma-activated chitosan (PAC) colloids for cancer treatment were obtained by using the cold atmospheric plasma technique. Chitosan solutions were irradiated by plasma ignited in argon gas and in a mixture of argon with nitrogen and oxygen gases in certain ratios. The structural modifications of chitosan and the chemical species generated in plasma were investigated by EPR, LC-MS/MS, XRD, DLS, and TGA methods.
View Article and Find Full Text PDFWater-choice experiments were conducted using glass eels of Anguilla japonica and A. marmorata, which coexist in subtropical East Asian rivers. The results of the present study, together with those of previous water-choice experiments, suggest that salinity enhances the odor preferences of glass eels.
View Article and Find Full Text PDFThe role of in regulating Notch signaling and neurogenesis has been extensively studied, with a particular focus on its effects on the peripheral nervous system (PNS). Previous studies based on a single loss-of-function allele of , , showed an antineurogenic effect on the peripheral nervous system (PNS), which revealed that the wild-type suppresses Notch signaling. In the current study, we examined whether this phenotype is consistently observed in loss-of-function mutations of Two more alleles, and , were shown to have an antineurogenic phenotype in the PNS.
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