Accuracy of the Dexcom G7 Continuous Glucose Monitoring Sensors in People with Diabetes Undergoing Hemodialysis (ALPHA-2 Study).

The accuracy of the latest generation Dexcom G7 sensors in individuals with diabetes undergoing hemodialysis has not previously been investigated. Participants with diabetes undergoing hemodialysis were recruited, with paired sensor glucose from Dexcom G7 recorded with plasma glucose analyzed in the laboratory, as well as the Freestyle Precision Pro glucometer and EKF Biosen C-Line analyzer. Ten adults (median age 64.

Chronic GIPR agonism results in pancreatic islet GIPR functional desensitisation.

Objective: There is renewed interest in targeting the glucose-dependent insulinotropic polypeptide receptor (GIPR) for treatment of obesity and type 2 diabetes. G-protein coupled receptor desensitisation is suggested to reduce the long-term efficacy of glucagon-like-peptide 1 receptor (GLP-1R) agonists and may similarly affect the efficacy of GIPR agonists. We explored the extent of pancreatic GIPR functional desensitisation with sustained agonist exposure.

NR2E3-Associated Retinopathy Presenting with Bilateral Choroidal Neovascularization.

Purpose: We describe an atypical presentation of an 11-year-old female with enhanced S-cone syndrome (ESCS).

Methods: Case report. The patient underwent a thorough ophthalmic examination and investigations such as colour fundus photography, optical coherence tomography, fundus autofluorescence, fluorescein and indocyanine angiography, an electroretinogram and genetic testing.

Low-carbohydrate diet score and chronic obstructive pulmonary disease: a machine learning analysis of NHANES data.

Background: Recent research has identified the Low-Carbohydrate Diet (LCD) score as a novel biomarker, with studies showing that LCDs can reduce carbon dioxide retention, potentially improving lung function. While the link between the LCD score and chronic obstructive pulmonary disease (COPD) has been explored, its relevance in the US population remains uncertain. This study aims to explore the association between the LCD score and the likelihood of COPD prevalence in this population.