Publications by authors named "T Y Kew"

is notorious for its intrinsic resistance to many commonly used antibiotics, making it a particularly challenging pathogen to treat. It often causes severe opportunistic infections in immunocompromised and hospitalized patients. The potential for this infection to become fulminant with high mortality rates in both adults and children necessitates a multidisciplinary approach.

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Objective: To assess the effects of COVID-19 vaccines in women before or during pregnancy on SARS-CoV-2 infection-related, pregnancy, offspring and reactogenicity outcomes.

Design: Systematic review and meta-analysis.

Data Sources: Major databases between December 2019 and January 2023.

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Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare inherited disease characterised by early arrhythmias and structural changes. Still, there are limited echocardiography data on its structural progression. We studied structural progression and its impact on the occurrence of major adverse cardiovascular events (MACE).

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Article Synopsis
  • Androgenic anabolic steroids (AAS) are largely misused by young men and are linked to earlier and more serious heart issues, especially regarding the atria.
  • Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) tend to show increased atrial arrhythmias and changes in P waves, indicating a male predisposition to these conditions.
  • Experiments on male mice revealed that exposure to the steroid 5α-dihydrotestosterone (DHT) exacerbates cardiac issues, particularly in those with a genetic makeup that reduces plakoglobin, leading to significant electrical remodeling in the heart.
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Skull base osteomyelitis is a not commonly encountered but potentially fatal consequence of untreated necrotizing otitis externa. Early recognition and appropriate treatment are crucial to prevent serious complications such as cranial nerve palsies, meningitis, and intracranial abscess formation. The case reports presented in this study provide a rich depiction of the clinical presentation, diagnostic challenges, and interventions employed.

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