Effectiveness study of recrystallisation method in pharmaceutical salt production from processed salt with zero waste concept.

Indonesia's vast archipelago offers abundant seawater resources, holding the potential for salt production. Salt, a vital commodity in human life, typically contains sodium chloride and impurities like Ca, Mg, SO, and K. Pharmaceutical salt is an industrial category adhering to pharmacopoeial standards regarding sodium chloride levels and impurity content, ensuring quality for drug preparations in Indonesia.

Poly lactic acid production using the ring opening polymerization (ROP) method using Lewis acid surfactant combined iron (Fe) catalyst (Fe(DS)).

LASC catalyst synthesis process was carried out using iron metal (Fe) and its characterization properties were tested. There are five stages carried out, namely, the manufacture of the LASC Fe(DS)3 catalyst, lactic acid dehydration, polycondensation of lactic acid into l-lactic acid oligomers (OLLA), depolymerization of oligomers into l-lactide, and the ROP process to convert l-lactide into Polymers. l-lactic acid (PLLA).

Novel series of tunable µOR modulators with enhanced brain penetration for the treatment of opioid use disorder, pain and neuropsychiatric indications.

Structural optimization of a previously reported agonist of µOR, PZM21 is described resulting in the discovery of a novel series of amides with at least 4-folds enhanced CNS penetration in rat. Furthermore, these efforts yielded compounds with varying levels of efficacy on the receptor ranging from high efficacy agonists such as compound 20 to antagonists, such as 24. The correlation between in vitro activation of µOR and relative activity in models of analgesia for these compounds is discussed.

Modelling and simulation of multicomponent acetone-butanol-ethanol distillation process in a sieve tray column.

Renewable energy sources are prospective solutions for addressing future energy needs arising from the ever-increasing population and dwindling petroleum reserves. Biobutanol is one of the most efficient biofuels for use as a mixture with motor vehicle fuels. Biobutanol is produced from the acetone-butanol-ethanol (ABE) fermentation process and is separated into the pure components via multicomponent distillation.

Optimization of process conditions for tannin content reduction in cassava leaves during solid state fermentation using .

Cassava leaves are a crucial source of alternative protein resources for both humans and livestock in developing societies in African and Asian countries that do not have easy access to available protein sources. Hence, cassava has the capacity to promote the economic development of these countries and provide food security. However, it has some disadvantages due to the anti-nutrient compounds present in its tissues, which limits the nutritional value of cassava leaves.