Publications by authors named "T Welsch"
Objective: The aim was to evaluate the sustainability of the pancreatic Enhanced Recovery After Surgery (ERAS) program and the effect of ERAS items on patient morbidity and hospital stay.
Background: The current ERAS guideline recommendations encompass 27 items to improve recovery after pancreatoduodenectomy (PD).
Methods: Patients who underwent pancreatic resection at the University Hospital Hamburg-Eppendorf between February 2016 and June 2023 were included.
Article Synopsis
- Surgical site infections (SSI) after pancreatoduodenectomy (PD) are a major concern, prompting the study to assess whether enhanced anti-infective prophylaxis (EAP) reduces SSI rates compared to standard prophylaxis.
- A retrospective analysis of 163 patients showed that those who received EAP had significantly lower SSI rates (14% vs. 37%) and urinary tract infections (8% vs. 24%) than those who received standard prophylaxis.
- The findings suggest that EAP not only reduces the incidence of SSIs but may also lower the risk of gastrointestinal complications post-surgery, with age over 67 identified as a significant SSI risk factor.
Background And Aims: This study sought to determine the value of patient-derived organoids (PDOs) from esophago-gastric adenocarcinoma (EGC) for response prediction to neoadjuvant chemotherapy (neoCTx).
Methods: Endoscopic biopsies of patients with locally advanced EGC (n = 120) were taken into culture and PDOs expanded. PDOs' response towards the single substances of the FLOT regimen and the combination treatment were correlated to patients' pathological response using tumor regression grading.
Background: The potential risk and subsequent impact of serious complications after pancreatic and colorectal surgery can be significantly reduced through early recognition, correct assessment, and timely initiation of appropriate therapy. Serious gaming (SG) is an innovative teaching method that combines play with knowledge acquisition, increased concentration, and quick decision-making and could therefore be used for clinically oriented education.
Objective: This study aims to develop a case-based SG platform for complication management in pancreatic and colorectal surgery, validate the application by comparing game courses of various professional groups in the health care sector, and test the acceptance of the developed platform in the context of clinical education by measuring levels of usability and applicability within the framework of a validity and usefulness analysis.