Publications by authors named "T Wakiya"

Portal cavernoma cholangiopathy (PCC) is a complex condition associated with portal hypertension, particularly in patients with extrahepatic portal vein obstruction (EHPVO). Herein, we present a case of liver failure with PCC in a 55-year-old male successfully treated with living-donor liver transplantation (LDLT). The patient had a history of gastrointestinal bleeding and recurrence of cholangitis.

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Article Synopsis
  • NAD + is crucial for various cellular functions and lower levels may be linked to cancer, sparking interest in how it changes in cancer patients undergoing surgery.
  • This study analyzed NAD + dynamics in 99 patients with different digestive cancers by measuring blood samples and found that while NAD + levels stayed stable post-surgery, nicotinamide mononucleotide (NMN) levels dropped and recovered differently based on cancer type.
  • The research suggests that understanding individual NAD + levels could lead to personalized supplementation strategies for cancer patients during treatment.
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Alanine aminotransferase (ALT) is an enzyme that catalyzes the transfer of amino groups from alanine to ketoglutaric acid. ALT is an established marker of liver diseases. Occasionally, ALT levels may be abnormally low due to various factors, making accurate assessment difficult.

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Acute normovolemic hemodilution (ANH) is a useful intraoperative blood conservation technique. However, the impact on long-term outcomes in pancreatic ductal adenocarcinoma (PDAC) remains unclear. The present study investigated the impact of ANH on long-term outcomes in patients with PDAC undergoing radical surgery.

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A 72-year-old man was referred to our hospital for the examination of a pancreatic head mass. Abdominal computed tomography revealed a contrasted 8-cm-diameter tumor extending from the dorsal pancreatic head to the porta hepatis. The preoperative diagnosis was challenging due to the absence of specific imaging findings and the inability to perform a biopsy.

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