Publications by authors named "T W Weickert"
Primary carnitine deficiency may mimic hypertrophic cardiomyopathy and be mistakenly attributed to genotype-negative sarcomeric protein dysfunction in hypertrophic cardiomyopathy. Although rare, timely diagnosis may have significant implications on management and should prompt testing of family members.
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- - The study investigates the relationship between left ventricular hypertrophy (LVH) and ventricular arrhythmias in patients with mitral valve prolapse (MVP), as sudden deaths have been linked to increased ventricular mass.
- - Out of 629 participants, 22.4% exhibited LVH, with those having LVH showing a higher incidence of complex or frequent ventricular ectopy (cfVE) than those without LVH.
- - The findings indicate that LVH is not an independent risk factor for ventricular arrhythmia in MVP; rather, the risk is more closely associated with certain mitral valve features and heart failure conditions.
Purpose: Antipsychotic-induced prolactin elevation may impede protective effects of estrogens in women with schizophrenia-spectrum disorders (SSD). Our study sought to confirm whether the use of prolactin-raising antipsychotics is associated with lower estrogen levels, and to investigate how estrogen and prolactin levels relate to symptom severity and cognition in premenopausal women with SSD.
Methods: This cross-sectional study included 79 premenopausal women, divided in three groups of women with SSD treated with prolactin-sparing antipsychotics (n = 21) or prolactin-raising antipsychotics (n = 27), and age-matched women without SSD (n = 31).
Background: Certain antipsychotics elevate prolactin levels in patients with schizophrenia spectrum disorders (SSD), potentially affecting cognition, symptoms, and hormone levels. This study examines the association between prolactin, testosterone, and estrogen and cognition and symptoms in men with SSD, considering antipsychotic medication.
Methods: This cross-sectional study included 128 men with SSD and 44 healthy men from two trials.