Publications by authors named "T W Viola"
Background: Interventions to promote mental health in paediatrics need to be effective, especially in crisis contexts. This systematic review proposes to compile and analyse the findings of nonpharmacological interventions conducted in samples of children and adolescents during the COVID-19 pandemic, focusing on mental health.
Methods: The research was carried out in PsycINFO, PubMed and Web of Science databases for empirical studies, including interventions in which measures of outcome variables were collected at least twice (pre and post).
Article Synopsis
- - The study aimed to review and meta-analyze RNA sequencing research comparing brain tissue from Alzheimer's disease patients to control subjects, focusing on study quality and identifying important genes and pathways linked to the disease.
- - Researchers examined 3,266 published studies and included 24 that met their criteria, discovering 571 differentially expressed genes in the temporal lobe and 189 in the frontal lobe, highlighting pathways like "Tube morphogenesis" and "Neuroactive ligand-receptor interaction."
- - The review faced challenges due to study differences and limited data but emphasizes that thorough methods are crucial for understanding Alzheimer's transcriptomic changes, which can help in the development of biomarkers and treatments.
Association between hair cortisol concentration and acute stress symptoms in family members of critically ill patients: a cross-sectional study.
Crit Care Sci
October 2024
Article Synopsis
- - The study aimed to explore the link between hair cortisol levels and acute stress symptoms in family members of critically ill patients in Brazil.
- - Researchers surveyed 110 family members, revealing that 80% experienced acute stress symptoms, but found no significant difference in cortisol levels between stressed and non-stressed individuals (p = 0.419).
- - The only factor significantly related to stress symptoms was the patient's alertness during the interview, indicating that prior cortisol levels may not predict acute stress in these family members.
Symptoms of depression and lifestyle in adolescents: A network analysis.
Trends Psychiatry Psychother
September 2024
Purpose: Life experiences that could either promote or attenuate depression have primarily been studied in adults. Therefore, we investigated the association between lifestyle factors and symptoms of depression in adolescents.
Design And Setting: A cross-sectional study was carried out in Brazilians.