Publications by authors named "T Visser"

Investigations into whether playing action video games (AVGs) benefit other tasks, such as driving, have traditionally focused on gaming experience (i.e., hours played).

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Nocturnal blood pressure (BP) shows the highest predictive power for cardiovascular events. However, there is a poor reproducibility of personalized dipping patterns in single individuals. We hypothesize that changes in body position during sleep cause variations in hydrostatic pressure,leading to incorrect BP values and dipping classifications.

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Article Synopsis
  • Brugada Syndrome (BrS) is a serious heart condition that can cause sudden cardiac death and is linked to mutations in the SCN5A gene, which affects sodium channels in the heart.
  • Researchers created human induced pluripotent stem cell (hiPSC) lines with a specific BrS mutation (c.845G>A or p.R282H) to better understand its effects.
  • The study compares two hiPSC lines: one with the mutation on the same gene copy as another polymorphism (c.1673A>G or p.H558R) and one with it on the opposite gene copy, providing a model to investigate their physiological impacts.
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Background: Testing and treating symptomatic malaria cases is crucial for case management, but it may also prevent future illness by reducing mean infection duration. Measuring the impact of effective treatment on burden and transmission via field studies or routine surveillance systems is difficult and potentially unethical. This project uses mathematical modeling to explore how increasing treatment of symptomatic cases impacts malaria prevalence and incidence.

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In malaria-endemic countries, private retail outlets are a major source of antimalarials for individuals experiencing an acute febrile illness. However, there remains a challenge in how the decision to dispense the drugs is made. The lack of malaria diagnostic tools in the retail sector leads to a presumptive approach to diagnosis and overuse of ACTs.

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