[The association of hemostasis system genes with the development of ischemic stroke in patients under the age of 50 years].

Aim: To study an influence of polymorphic variants of hemostasis system genes on the risk of ischemic stroke (IS) in patients of the Slavic population under the age of 50 years.

Material And Methods: Ninety-two patients (19 women and 73 men), aged 18-50 years, were examined. The diagnosis of stroke was confirmed by neuroimaging (CT or MRI) in all patients.

[Early diagnosis of risk for developing calcium oxalate urolithiasis].

Aim: To identify risk groups for calcium oxalate urolithiasis among healthy individuals and patients with urolithiasis in the Russian population using molecular genetics.

Materials And Methods: The study comprised 72 patients with calcium oxalate urolithiasis (study group) and 189 healthy adults from the general Russian population (control group). The study group consisted of 39 (54.

[Associations between chronotype, road accidents and polymorphisms in genes linked with biological clock and dopaminergic system].

Unlabelled: Public transport driving is a highly demanding activity requiring high skills and responsibility. Shift work, problems with regular sleep schedule negatively impact psychomotor reactions, cognitive functions and ability to react appropriately to the changing environment. For professional drivers all these factors may lead to the increased risk of a road accident.

[Genetic risk factors for recurrence-free urolithiasis in the russian population].

Purpose: Search for and identification of possible associations of recurrence-free urolithiasis with polymorphisms of urolithiasis candidate genes in the Russian population.

Materials And Methods: The study involved 43 patients with recurrence-free urolithiasis, 13 (30.2%) women and 30 (69.

[Polymorphisms in Sleep and Cognitive Function Related Genes are Associated with Vehicle Crash History in Shift Working Bus Drivers].

Bus driving is a highly responsible profession. It requires constant engagement of attention and cog- nitive resources as well as vigilance and resistance to disruption of sleep- rhythms. There is ongoing research of genetic correlates of these individual characteristics.