[Transmission of "regenerative" information by lymphocytes from rats with extensive intestinal resections].

Lymphocytes from male F1 rats (August X black Wistar) with a resected half of the small intestine (10 cm after stomach) are capable to stimulate the mitotic activity in the epithelium of small intestinal and esophageal crypts in syngeneic recipients. The correlation of the mitotic phases in experimental animals remained unchanged whereas the number of cells in experimental recipients' crypts significantly increased, thereby attesting to genuine stimulation of the proliferation. Lymphocytes from sham-operated rats failed to demonstrate such a property.

[Lymphoid regulation of the proliferative stage in regeneration of the intestines and esophagus of rats].

After the removal of a half of small intestine in the rats, the lymphocytes acquired the ability to stimulate the mitotic activity of crypts of the small intestine, large intestine and oesephagus in syngenic recipients. The ratio of mitotic phases in the experimental animals suffered no changes, the number of cells in the crypts increased reliably thus suggesting the true stimulation of proliferation. The lymphocytes of pseudooperated rats had no such ability.

[Reparative processes in the rat stomach in long-term nonhealing experimental ulcers].

Gastric ulcer in rats was induced by exposure to acetic acid according to the method of Okabe. The reparative processes in the ulcerative defect zone of gastric mucosa, in adjacent and distant fundic glands were studied by the quantitative methods (determination of the cellular composition of the glands, of the diurnal number of DNA-synthetising cells, mitoses). It was established that on the 15th day after induction of the ulcer, the level of proliforation in the zone was significantly increased as compared to that in intact controls, while in distant areas it remained unchanged.

[Role of injury in the appearance of "activated" smooth muscle cells].

The ultrastructure of the smooth muscle tissue was studied in the posterior vena cava in rats after the disturbance of blood outflow, in the stomach following resection of half of its fundus and cecum after constriction of its ascending limb. "Activation" of the smooth muscle was found to reflect the stage of the cell ultrastructure injury, and then the processes of intracellular regeneration. Analysis of the correlation between the DNP-synthesizing and the "activated" cells showed the latter to be of local origin, from the differentiated myocytes.

[NAG-infection in grass frogs (Rana temporaria) subjected to hypothermia].

Rana temporaria kept under hypothermic conditions approaching anabiosis were inoculated with NAG-vibrios and examined clinically, bacteriologically, histologically, and electron microscopically. Oral inoculation of hypothermic frogs with NAG-vibrios resulted in 18 to 24 hours in the development of acute NAG-infection resembling the cholera-like syndrome, and characterized by general intoxication and local enteropathogenic effects. NAG-vibrios persisted in the frog gastrointestinal tract for a long time after the cessation of the acute period of the disease.