Psoralen-photosensitized damage of rat peritoneal exudate cells.

Psoralen-sensitized photodamage (PUVA) of rat peritoneal exudate cells was investigated. Quartz-activated luminol-dependent chemiluminescence (ChL) was registered and the amount of trypan-positive cells was determined. Irradiation of peritoneal exudate cells in the presence of psoralen resulted in a dose-dependent monotonous inhibition of ChL.

[Data for the substantiation of the maximum permissible exposure level of armos fiber dust in the air of the work area].

The 'Armos' fibre dusts are characterized by low cytotoxicity, absence of fibrogenicity, display non-toxic properties in single exposures with no skin-irritating and sensibilizing effects. In repeated introduction into the stomach, the trachea, and if inhaled, these dusts displayed weak toxic properties. Dust concentrations at 10 mg/m3 are in proximity to the threshold one.