Investigation of the microflora and the principles of treatment of infected open tissue defects.

Treatment of chronic defects of the body remains a difficult problem. Despite the achievements in reconstructive surgery, the failure incidence is high. Infection in the chronic defect region plays the leading role in the pathogenesis.

Several aspects of formation of auto-transplant and re-transplant vascular pedicle.

The purpose of the work was the simplification of technical side of autotransplantation and replantation by pre-preparation of vascular pedicle. 173 patients were observed and treated. Microsurgical autotransplantation of tissues was done in 29 cases, fingers autotransplantation in 44 cases (35 patients), fingers replantation in 66 cases (38 patients), replantation of thick parts of extremities in 34 cases (3 patients).

Possibilities of application of composite bone-soft tissue complex in reconstructive surgery.

Hereby the method of formation of bone-soft tissue complex with its future application in reconstructive surgery is presented. Treatment of spacious defects of human body with soft tissue lost as well as with bone injury is considered as critical problem in contemporary surgery. Even today, there is no final reference regarding the particular sort of flat to be applied in each specific case.

[Possibilities of a compound bone and soft tissue complex in reconstructive surgery].

The method of forming a bone and soft tissue complex for reconstructive surgery is presented. Sixty-eight transplantations of compound flaps of soft tissues, muscles and bones including ones on microvascular anastomosis were performed in 66 patients. Good functional and esthetic results were seen in 86.

[Methodological aspects of studying chemical preparations in a model of experimental influenzal infection].

Some methodologic approaches have been developed permitting most exhaustive characterization of antiviral and antitoxic activity of drugs in mice infected with toxigenic and nontoxigenic influenza A virus strains.