[Vertebral pain syndrome and quality of life in senior women with vertebral fractures depending on their quantity and localization.].

The features of vertebral pain (VP) and quality of life in postmenopausal women were analyzed depending on the number and location of vertebral fractures (VF). It was found that the intensity of pain in thoracic and lumbar spines, according to McGill pain index, was significantly higher in patients with two or more VF compared to women without any fractures, and absence of differences in subjects with a single VF. Most indices of 11-component Numerical Rating Scale at the thoracic spine were significantly higher only in females with two or more VF.

[Marital status and place of living as social determinants of vertebral pain syndrome and disturbance of life quality in women of older age groups.].

In order to study the role of the marital status and place of residence, as the social determinants of the development of vertebral pain syndrome and related disorders of life activity, the results of a survey of 148 postmenopausal women aged 50-69 years were analyzed. Respondents were divided into groups depending on their marital status (living in a family with husbands and other relatives, only with husbands or alone) and places of residence (in rural or urban areas). The results of this study suggest that family status and place of residence in women of older age groups do not directly influence on the back pain, however they contribute to impairment of vital functions associated with back pain, in particular, psychological state, general activity, working capacity, and also stipulate a higher frequency of requests for medical care and hospitalizations.

[Features of vertebral pain syndromes in older women depending on the duration of postmenopausal period and bone mineral density indices].

We have analyzed the vertebral pain syndrome (VPS) rate in 2 844 women aged 40-89 years, divided into groups according to the period of life (reproductive, perimenopausal and postmenopausal (PMP)) and evaluated the relationship between VPS frequency and indices of bone mineral density (BMD). It was found that the frequency of VPS during different physiological periods of woman life ranges from 84,1 to 94,4 %, with significant increase when the PMP period is more than 20 years compared with women in reproductive and early postmenopausal periods. The significant increase of the VPS frequency in thoracic and lumbar spines starts from 1-3 years of PMP and is retained at higher level for all subsequent periods of PMP.

[AGE AND SEX FEATURES OF BONE MINERAL DENSITY IN RATS].

In vivo assessment of bone mineral density (BMD) and bone mineral content (BMC) indices gives an objective description of the possible rates of bone loss during aging and various diseases, as well as response to treatment by various drugs, affecting bone metabolism. This study was conducted on 376 Wistar rats of both genders, divided into 12 age groups using the method of dual-energy X-ray absorptiometry. Studying the parameters of BMD and BMC depending on age and sex has found no bone mass opeak) in rats of both sexes.