[Efficacy of medicamentous treatment of transient premenstrual phlebopathy of lower limbs].

Aim: The purpose of the study was to examine changes of the clinical pattern and the great saphenous vein in women with premenstrual leg heaviness and distal oedema in repetitive 15-day courses of micronized purified flavonoid fraction, initiated in the second half of the menstrual cycle.

Patients And Methods: A total of 39 parous women (mean age 31.3±7.