Complex Inhibitor Protection of Some Steels in Hydrochloric Acid Solutions by 1,2,4-Triazole Derivatives.

The behavior of low-carbon steels (LCSs), a high-strength steel and a nickel-chromium alloy in HCl solutions in the presence of N-containing organic substances has been studied. N-containing organic substances that comprise 1,2,4-triazole in their structure (substance I and substance II) provide comprehensive protection of various steel grades from corrosion and hydrogen absorption by the metal bulk in HCl solutions under both isobaric and isochoric conditions. All the compounds studied reduce, to varying degrees, the concentration of hydrogen adsorbed and absorbed by steel in HCl solutions.

Features of Highly Homologous T-Cell Receptor Repertoire in the Immune Response to Mutations in Immunogenic Epitopes.

CD8+ T-cell immunity, mediated through interactions between human leukocyte antigen (HLA) and the T-cell receptor (TCR), plays a pivotal role in conferring immune memory and protection against viral infections. The emergence of SARS-CoV-2 variants presents a significant challenge to the existing population immunity. While numerous SARS-CoV-2 mutations have been associated with immune evasion from CD8+ T cells, the molecular effects of most mutations on epitope-specific TCR recognition remain largely unexplored, particularly for epitope-specific repertoires characterized by common TCRs.

T-Cell Receptors Cross-Reactive to Coronaviral Epitopes Homologous to the SPR Peptide.

The COVID-19 pandemic caused by the rapid spread of the novel coronavirus SARS-CoV-2, has promoted an interest in studying the T-cell immune response. It was found that the polyclonal and cross-reactive T-cell response against seasonal coronaviruses and other SARS-CoV-2 strains reduced disease severity. We investigated the immunodominant T-cell epitope SPRWYFYYYL from the nucleocapsid protein of SARS-CoV-2.

Complex Protection of Some Steels in Sulfuric Acid Solutions by 1,2,4-Triazole Derivatives.

The corrosion behavior of steels of various grades in sulfuric acid solutions with the addition of nitrogen-containing corrosion inhibitors has been studied. Compounds containing the 1,2,4-triazole moiety effectively protect low-carbon (St3, St20, 08PS), high-strength (70S2KhA), and stainless steels (1Kh18N9T) not only from corrosion but also from the hydrogen penetration into the metals in concentrated sulfuric acid solutions. In some cases, the degree of steel protection from corrosion by these compounds exceeded 99%.

Thin Films of a Complex Polymer Compound for the Inhibition of Iron Alloy Corrosion in a HPO Solution.

The etching of iron alloy items in a HPO solution is used in various human activities (gas and oil production, metalworking, transport, utilities, etc.). The etching of iron alloys is associated with significant material losses due to their corrosion.