Background: Clinical trials have led to the development of new and effective therapies for many dermatologic conditions. To our knowledge, there is no published study that has quantified and described the degree of involvement in clinical trials among academic dermatologists and their university affiliates.
Objective: The purpose of this study was to characterize the involvement of academic dermatology departments in clinical trials research.
The study was carried out in 55 females with breast cancer stage III-IV, aged 35-77 yrs. The patients received radiation and standard courses of CMF, or CAF, or CMF+trastuzumab, or carboplatin+vepesid, or taxotere+epirubicin, or mustoforan. Radiation was administered in fractionated single focal doses of 3 Gy.
View Article and Find Full Text PDFPolymerase chain reaction and sequence analysis were used to screen Ehrlichia and Anaplasma DNA in 900 specimens of Ixodes ticks of four genera (Dermacetor, Haemaphysalis, Ixodes, and Hyalomma) collected on 14 administrative territories of Russia and Kazakhstan. Anaplasma phagocytophilia DNA was detected and identified in Ixodes persulcatus ticks gathered in the Altai and Primorye Territories. Ehrlichia muris DNA was genotyped in the I.
View Article and Find Full Text PDFZh Mikrobiol Epidemiol Immunobiol
October 2004
The presence of Rickettsia hulinii was detected in ticks of the Haemaphysalis concinna species in the Asiatic part of Russia. It was the first detection of these rickettsiae outside the territory of the Chinese People's Republic. This tick is spread over a broken area and may occur in different regions of Eurasia.
View Article and Find Full Text PDFTreatment and prognosis of neurooncolical patients are largely determined whether tumor is a primary brain neoplasm or metastasis. Out of 284 brain cancer patients treated at the Institute's Clinic, 262 had primary tumors and 22--metastases from various sites. Combined therapy was given to 273: surgery--241, radiotherapy--273 and polychemotherapy--263.
View Article and Find Full Text PDF