[Effectiveness of the elimination of lipid peroxidation products in various methods of detoxication therapy of patients with traumatic shock].

The shockogenous trauma is followed by a considerable accumulation of lipid peroxidation products in the patient's organism. The most effective of all the measures used for the detoxication was found to be extracorporal use of the donor spleen which resulted in lower content of lipid peroxidation products in blood plasma immediately after the procedure. The maximum effect was observed 1 hour later and persisted during one day after treatment.

[Energy metabolism in skeletal muscles in experimental traumatic shock].

Content of ATP and adenylate nucleotides was not markedly altered in rats during a traumatic shock induced by Cannon's procedure involving an impairment of skeletal muscles. Energy potential and content of creatine phosphate were only slightly decreased in these tissues, while the level of lactate and the lactate/pyruvate ratio were increased at the terminal phase.

[The state of energy metabolism in the rat liver after a single acute hemorrhage].

A system of adenine nucleotides and redox state of liver cells as well as activities of dehydrogenases of the tricarbonic acid cycle and of cytochrome oxidase in liver cell homogenates were not altered after an acute single hemorrhage in rats even though the process run into the step of circulation decompensation (AP 40 mm Hg).

[Preservation of liver mitochondria function in hemorrhage-resistant rats during severe long-term hypotension].

In contrast to the reported data evidencing early impairment of the liver mitochondrial function in the Wiggers model of hemorrhagic shock at the arterial blood pressure 30-40 mm Hg, lasting not over 6 h, a group of hemorrhage-resistant rats was discovered. In these rats, the lifetime was about 20 h, with the blood pressure being the same as indicated above. Rectal temperature decreased to 24-25 degrees C during shock.