[Impact of active detection and treatment of patients with tuberculosis on fatal outcomes].

The influence of medical factors, such as active detection of the disease and therapeutic efficiency within the first-year follow-up, on the outcome of tuberculosis was studied. It was ascertained that about half the patients with active tuberculosis could not be undetected if goal-oriented measures to attract persons to screening were not made. Fatal outcomes were more common in patients with untimely diagnosed disseminated tuberculosis with bacterial isolation and decay.

[Prediction of the rate of tuberculosis mortality (calculation methodology)].

Correlation and cross-correlation analyses were used to predict the rate of mortality. The equations of linear and multiple regressions were derived. The indices and factors, which are related and affect the rate of tuberculosis mortality, are defined.

[Influence of seasonal and environmental factors on the incidence of tuberculosis].

The seasonal fluctuations of the incidence of respiratory tuberculosis were studied among 3205 new cases aged above 18 years, registered in the Voronezh Region in 1998-2000. The study of the seasonal fluctuations by the dates of filling in notices about a patient with the diagnosis of active tuberculosis established for the first time in his/her life revealed no regularities. A procedure has been proposed for studying the seasonal fluctuation in the development of tuberculosis by the period the early clinical symptoms of the disease occurred.