On-surface synthesis of phthalocyanines with extended π-electron systems.

Expanded phthalocyanines are a promising class of materials for optoelectronic applications, owing to their unique properties and versatile metal coordination reactivity. The expansion of their π-electron systems and resulting red-shifted absorption are of particular interest for achieving broader applications. Here, we report the on-surface synthesis of metallo-phthalocyanines with extended electron systems and an open-chain polycyanine from ortho-dicarbonitrile precursors on Ag(111) and Au(111), studied by scanning tunneling microscopy (STM) and X-ray photoelectron spectroscopy (XPS).

Comparative Pharmacoeconomic Effectiveness of Interleukin-17 Inhibitors for the Treatment of Ankylosing Spondylitis.

The objective of this study was to compare the clinical efficacy and cost-effectiveness of IL-17 inhibitors (SEC, IXE, NTK) in the treatment of adult patients with ankylosing spondylitis (AS) in the healthcare system of the Russian Federation. Materials and methods. The study is a sub-analysis of a previously published systematic review and network meta-analysis of the comparative efficacy of biologics in adult patients with AS in the Russian Federation.

[Activity of ankylosing spondylitis in women within one year after childbirth].

Aim: To assess the dynamics of activity of ankylosing spondylitis (AS) during the year after childbirth, to identify predictors of high activity.

Materials And Methods: 75 pregnant with confirmed AS (modified New York criteria, 1984) were included for prospective observation. Of these, 44 women were followed up for 1 year after delivery.

[Achievement of clinical-laboratory and ASAS-partial remission in patients with early axial spondyloarthritis according to the ESAC cohort at the 3rd year of follow-up].

Background: According to the treat-to-target strategy for spondyloarthritis (SpA), the main goal is to achieve clinical remission or inactive disease. In 2001, the Assessment of Spondyloarhtritis International Society (ASAS) formulated the ASAS criteria for partial remission, and the Russian expert group for the study of SpA identified clinical-laboratory remission (no clinical manifestations of the disease that persists for 6 months in the presence of normal values of C-reactive protein and erythrocyte sedimentation rate), magnetic resonance imaging (MRI) remission and complete remission (a combination of clinical-laboratory and MRI remission).

Aim: To determine the frequency of achieving clinical-laboratory and ASAS partial remission in patients with early axial SpA (axSpA) at the 3rd year of follow-up.