Immunohistochemical Evaluation of Basal and Luminal Markers in Bladder Cancer: A Study from a Single Institution.

Background: Bladder cancer (BC) presents significant molecular diversity, which affects both prognosis and treatment results. Immunohistochemistry (IHC) facilitates the identification of molecular subtypes and their relationships with clinicopathological features.

Methods: We performed an IHC analysis on tissue samples from 107 BC patients, evaluating the expression of markers GATA3, CD44, CK5/6, and CK20.

Trends in use of tobacco and cannabis across different alcohol consumption levels in the United States, 2010-19.

Aims: People often drink alcohol and use other substances concurrently, increasing the risk of adverse health outcomes. Our aims were to: (i) assess temporal trends in tobacco and/or cannabis use by varying alcohol consumption levels and (ii) identify associated factors of polysubstance use in high-risk alcohol users.

Methods: We conducted a repeated cross-sectional study combining 2010-19 U.

Influential Factors in the Treatment of Infections at a Tertiary Hospital in Vietnam.

As an opportunistic pathogen, is often associated with severe respiratory infections. A study conducted in an ICU of a tertiary hospital in Vietnam, where infection management is relatively good, yielded only 18 clinical isolates of over 6 months. Though the number is small, treating infections is highly complicated.

Daily accumulation of marine litter in a clam culture area in Can Gio District, Ho Chi Minh City, Vietnam.

The health of humans, the economy, and the marine ecology are all seriously threatened by marine litter. Therefore, quantifying the scope of the issue is gaining more and more attention. Studying beach litter accumulation is one of the approaches to investigating its flows into the marine environment.

A case study of lethal neonatal CPT II deficiency: Novel insights from genetic analysis.

Introduction: Carnitine Palmitoyltransferase II (CPT II) deficiency encompasses a spectrum of disorders, with the lethal neonatal form (LNF) representing the rarest and most severe. While there are numerous gene variants that can cause CPT II deficiency, only 16 variants of these are known to be associated with LNF. This report presents the case of a neonatal male diagnosed with lethal CPT II deficiency, characterized by the presence of two heterogeneous variants.