Publications by authors named "T Unno"

Antibiotic resistance genes (ARGs) have been emerging as a concerning threat to both environment and public health. The continuous input of manure, irrigation water, and fertilizers increases the abundance of ARGs in agricultural environments. However, current risk assessments have focused on clinical settings, which are not applicable to environmental settings.

View Article and Find Full Text PDF
Article Synopsis
  • Enfortumab Vedotin (EV) is an effective treatment for advanced urothelial carcinoma (UC) patients who have already undergone other therapies, but there’s limited understanding of the factors that impact patient outcomes.
  • A retrospective study was conducted to identify clinical factors affecting progression-free survival (PFS) and overall survival (OS) in these patients, leading to the development of a new risk classification model based on identified prognostic factors.
  • The study found that high levels of C-reactive protein and hypercalcemia were significant predictors of patient outcomes, allowing for the classification of patients into three distinct risk groups, which showed notable differences in survival rates.
View Article and Find Full Text PDF

Various metabolic diseases caused by a high-fat diet (HFD) are closely related to gut microbiota dysbiosis and epithelial barrier dysfunction. Polycan, a type of β-glucan, is effective in treating anti-obesity and metabolic diseases caused by HFD. However, the effect of Polycan on dysbiosis and epithelial barrier damage is still unknown.

View Article and Find Full Text PDF

Introduction: The Amplatzer Vascular Plug (AVP) series enables precise positioning and high migration resistance, allowing embolization in short segments; however, inadequate embolization or recanalization may occasionally occur. We hypothesized that leaks may occur when AVPs are implanted in vessels with irregular lumen due to insufficient adherence to the vessel. This hypothesis was tested by experiments with a vascular model.

View Article and Find Full Text PDF