Publications by authors named "T Umeda"

Objective: The extent of resection (EOR) is an important prognostic factor for both low- and high-grade gliomas. Intraoperative MRI (iMRI) has been used to increase the EOR in glioma surgery. While a recent study reported differences between iMRI and early postoperative MRI (epMRI), their specific relationship to postoperative clinical symptoms remains unclear.

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Mammals can execute intended limb movements despite the fact that spinal reflexes involuntarily modulate muscle activity. To generate appropriate muscle activity, the cortical descending motor output must coordinate with spinal reflexes, yet the underlying neural mechanism remains unclear. We simultaneously recorded activities in motor-related cortical areas, afferent neurons, and forelimb muscles of monkeys performing reaching movements.

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The digestion behavior of a food bolus comprising bread particles in the presence of gastric peristalsis remains poorly understood. This study systematically investigated the effect of bread type on in vitro gastric digestion behavior using a human gastric digestion simulator (GDS) that is capable of quantitatively simulating gastric peristalsis. A food bolus consisting of 60 g of bread (white bread, bagel, German bread, French bread, or croissant), 15 mL of a simulated salivary fluid, and 240 mL of a simulated gastric fluid was used for gastric digestion in vitro using the GDS for 3 h at 37 °C.

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Article Synopsis
  • Tectal glioma (TG) is a rare, lower grade glioma primarily found in children, but this study identified cases in older patients, with a median age of 30.5 years.
  • The study reviewed six TG cases treated at an institute from 2005 to 2023, highlighting diverse diagnoses including pilocytic astrocytoma and high-grade gliomas, based on histological evaluations.
  • Genetic analysis revealed distinct mutations in two cases, emphasizing the importance of thorough diagnostics, including molecular evaluation, to understand the varied characteristics of TG.
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Article Synopsis
  • - The study explored the use of 123I-iomazenil SPECT imaging to assess neuronal viability and its correlation with cognitive function in adult patients with moyamoya disease (MMD) before and after surgical revascularization.
  • - Sixteen adult MMD patients underwent cognitive assessments using the Mini-Mental State Examination and Frontal Assessment Battery, along with 123I-IMZ and 123I-iodoamphetamine SPECT scans to analyze brain activity and blood flow.
  • - Results showed normal cognitive function in most patients pre-surgery, while those with pre-existing cognitive dysfunction exhibited lower 123I-IMZ uptake; cognitive performance and imaging results improved post-surgery for this group, indicating potential benefits of
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