Publications by authors named "T Tuboi"

Introduction: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders in humans. The most frequent CAH variant is 21-hydroxylase deficiency. Patients with 21-hydroxylase deficiency require long-term glucocorticoid replacement treatment.

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Article Synopsis
  • The 2',5'-oligoadenylate (2-5A) is a key player that inhibits protein translation in vertebrate cells by activating RNase L, an endoribonuclease.
  • This 2-5A mechanism is crucial in the body's defense against viral infections through interferon pathways.
  • The study discusses the creation of modified 2-5A derivatives, their engagement with RNase L, and their stability in biological settings.
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Purpose: To evaluate extraocular muscle enlargement (EME) in dysthyroid ophthalmopathy.

Methods: EME was assessed by orbital computed tomography (CT) in 573 patients with dysthyroid ophthalmopathy in order to investigate the frequency and exact location of EME and the clinical features of related ocular symptoms in patients with dysthyroid ophthalmopathy.

Results: Of the 573 patients examined, 187 patients (38%) showed evidence of EME on CT images.

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Pulsed-field gel electrophoresis (PFGE) is a highly discriminating tool for molecular typing, but the conventional PFGE protocol is time consuming. This paper describes a rapid method of PFGE for Listeria monocytogenes that yields results within 2 days.

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; Buccal juice of the sea hare Aplysia juliana was found to degrade algal polysaccharides. The optimal enzyme composition for protoplast preparation from Undaria pinnatifida was protein at 48 µg/ml buccal juice from sea hare, 10 mg/ml cellulase Onozuka-RS, 0.4 M NaCl, 0.

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