CT texture analysis for the prediction of KRAS mutation status in colorectal cancer via a machine learning approach.

Purpose: This study aimed to investigate whether a machine learning-based computed tomography (CT) texture analysis could predict the mutation status of V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) in colorectal cancer.

Method: This retrospective study comprised 40 patients with pathologically confirmed colorectal cancer who underwent KRAS mutation testing, contrast-enhancement CT, and F-fluorodeoxyglucose (FDG) positron emission tomography (PET) before treatment. Of the 40 patients, 20 had mutated KRAS genes, whereas 20 had wild-type KRAS genes.

[Survival of glottic carcinoma patients treated with definitive radiation therapy: value of the Sixth edition of the UICC TNM staging system].

Purpose: To evaluate the survival of glottic carcinoma patients treated with radiation therapy (RT). The predictive value of the new sixth edition of the UICC staging system was also evaluated.

Methods And Materials: 193 patients with T1-2N0 glottic squamous cell carcinoma, classified according to the fifth edition of the UICC staging system, were treated with definitive RT.

[Clinical evaluation of esophageal cancer complicated with head and neck cancer].

We prospectively investigated endoscopic findings of the upper digestive tract in patients with head and neck (H & N) cancer, from 1992 to 2001. Of 687 patients with H & N cancer, esophageal cancers were found to affect 74 patients (10.8%).

[Clinical evaluation of gastric diverticulum on indirect radiograph for gastric mass survey].

The aim of this study was to evaluate the clinical conditions of gastric diverticulum. Fifty-four patients with gastric diverticulum (20 men and 34 women among 34,314 patients who underwent medical check-ups) were evaluated on indirect radiographs, for an incidence of 0.16% among the total number of examined cases, a rate lower than that of previous reports.