Publications by authors named "T Toyoda"

L-type calcium channel antagonists are uncommon causes of myoclonus, and the underlying mechanism remains unclear. Here, we report a case of parkinsonian syndrome with deterioration of preexisting myoclonus after nifedipine use. A 96-year-old woman was administered a single dose of sustained-release nifedipine for chest pain.

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Background: Primary graft dysfunction (PGD) is the leading cause of short- and long-term mortality associated with lung transplantation. The impact of pretransplantation blood transfusions for recipients is not fully elucidated.

Methods: This is a retrospective review of 206 consecutive lung transplantations performed at a single academic center (Northwestern University Feinberg School of Medicine, Chicago, IL) from January 2018 to July 2022.

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Background: According to a large-scale clinical trial in Japan, segmentectomy for small peripheral non-small cell lung cancer has an advantage over lobectomy in terms of overall survival, while it could also increase the incidence of local recurrence. In ipsilateral reoperations, intrathoracic adhesions from a previous surgery increase the risk of lung injury and bleeding, which may result in intraoperative and postoperative complications. The ability of oxidized regenerated cellulose (ORC) sheets to prevent postoperative adhesions has been demonstrated in the abdomen, and the same effect is expected in the thoracic region.

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Background: Segmentectomy has been recognized as the standard procedure for small peripheral lung cancer; however, it has been shown that loco-regional relapse is more common with segmentectomy than with lobectomy. This study aims to investigate the long-term outcomes and loco-regional relapse patterns in patients with clinical stage IA (c-IA) non-small cell lung cancer (NSCLC) after segmentectomy and compare them with those after lobectomy.

Methods: We retrospectively compared the long-term outcomes of 115 patients who underwent segmentectomy for c-IA NSCLC with those of 292 patients who underwent lobectomy between January 2008 and December 2015.

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Article Synopsis
  • Right heart remodeling is commonly observed in patients suffering from severe COVID-19-related acute respiratory distress syndrome (ARDS), but there is limited information on the recovery of the right heart following lung transplantation for these patients.
  • A study at Northwestern University analyzed data from 36 patients who underwent lung transplantation for COVID-19-related ARDS between June 2020 and June 2022, finding that none of the patients died within 90 days, and the 1-year survival rate was 88.8%.
  • Postoperative evaluations revealed significant improvements in right ventricle (RV) size and function, as well as reduced pulmonary artery pressure, indicating that right heart recovery can occur relatively quickly after lung transplantation in this specific patient population.
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