Publications by authors named "T Tomczyk"

Pedunculagin is a widely abundant ellagitannin found in the plant kingdom, with a chemical structure featuring two hexahydroxydiphenoyl units linked to a glucose core. It has demonstrated various biological activities, including anti-cancer, anti-inflammatory, and anti-bacterial effects. This review aims to summarize the bioactivities, chemistry, and health-promoting properties of pedunculagin and plant preparations containing it.

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This study aimed to assess changes in the morphology of the retina and cornea in patients treated and hospitalized during the acute active phase of SARS-CoV-2 infection. A total of 24 patients with symptomatic early COVID-19 disease and 38 healthy participants from a control group were enrolled in our study. Among them, 20 received oxygen therapy at flow rates ranging from 1-10 L, while four received high-flow intranasal oxygen therapy (HFNOT).

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Article Synopsis
  • - The study aimed to evaluate and compare the eye parameters (optic nerve, retina, and retinal vessels) between recovered COVID-19 patients and healthy individuals using optical coherence tomography angiography (OCT-a).
  • - A total of 156 eyes from post-COVID-19 patients and 98 eyes from a control group were examined using various OCT methods, focusing on different retinal metrics and ensuring only one eye's data from each person was analyzed.
  • - The results showed no significant differences in key eye measurements, suggesting that recovered COVID-19 patients did not have notable changes in their eye structure compared to healthy individuals.
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Background: Anaesthesia is neurotoxic in developing primates. Retrospective clinical studies show a correlation between exposure to anaesthesia during infancy and the occurrence of learning disorders (LD). Prospective studies failed to detect any influence of a single exposure to anaesthesia on neurodevelopment.

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Hypothyroidism frequently manifests with altered mood and disturbed cognition. Kynurenic acid may influence cognition through antagonism of N-methyl-d-aspartate receptors (NMDA) and α7 nicotinic receptors. In here, thyroid hormones effects on kynurenic acid synthesis in rat cortical slices and on kynurenine aminotransferases (KATs) activity in semi-purified cortical homogenates were studied.

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