A novel infrasound and audible machine-learning approach to the diagnosis of COVID-19.

Background: The coronavirus disease 2019 (COVID-19) outbreak has rapidly spread around the world, causing a global public health and economic crisis. A critical limitation in detecting COVID-19-related pneumonia is that it is often manifested as a "silent pneumonia", pulmonary auscultation that sounds "normal" using a standard stethoscope. Chest computed tomography is the gold standard for detecting COVID-19 pneumonia; however, radiation exposure, availability and cost preclude its utilisation as a screening tool for COVID-19 pneumonia.

["Concentrated KCL-free" hospital: stopping the use of potassium chloride concentrated ampoules in clinical departments and units--steps in implementing a new policy for increasing safety of drug therapy].

Background: About one third of deaths of hospitalized patients associated with adverse drug reactions are due to hyperkalemia caused by administration of solutions that contain too high a concentration of potassium. Frequently, the reasons for these phenomena are mistakes that occur when the potassium obtained from the concentrated ampoule is diluted in the solution by department nurses. In the literature it is recommended to refrain from preparing such solutions in the departments, and to use premixed solutions which contain a known concentration of the potassium.

Comparison of efficiency and preference of metal and plastic spacers in preschool children.

Background: The metal NebuChamber valved holding chamber (VHC) has gained wide acceptance among children with asthma. Due to its nonelectrostatic properties and larger volume, the 250-mL, metal NebuChamber delivers a greater mass of aerosol to a filter at the mouth compared with the commonly used 150-mL polypropylene AeroChamber VHC. Such in vitro results have been used to suggest that this may provide increased efficacy with the NebuChamber.

Safety of inhaled corticosteroids delivered by plastic and metal spacers.

Background: Because of its non-electrostatic properties the metal Nebuchamber (NC) valved holding chamber (VHC) delivers a greater mass of aerosol to the mouth than the polypropylene Aerochamber (AC) VHC. Delivery of more aerosol to the lungs may also increase systemic absorption of inhaled corticosteroids (ICS) and hypothalamo-pituitary-adrenal (HPA) suppression.

Methods: Thirty children (mean 4.