Publications by authors named "T Thivakaran"
Tetanus, caused by , remains a serious but preventable infection, with global incidence significantly reduced through widespread vaccination. We present the case of a 51-year-old man who developed severe tetanus following a minor nail prick injury, despite receiving tetanus toxoid and antibiotics. His condition rapidly progressed to trismus, hyperreflexia, continuous spasms, autonomic instability, and respiratory failure, requiring mechanical ventilation.
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- Organophosphate poisoning, specifically from chlorpyrifos, can lead to delayed neurological issues, including a rare form of pure motor neuropathy without sensory loss.
- A case study of a 15-year-old girl demonstrated cholinergic crisis after ingesting chlorpyrifos, with subsequent development of neurological symptoms like motor neuron signs and urinary incontinence weeks later.
- The study suggests that chronic neurotoxicity from OPs depends on multiple factors, and the resulting damage primarily affects motor functions, potentially leading to severe complications like myelopathy.
Article Synopsis
- Guillain-Barre syndrome (GBS) can have relapses despite often being a one-time illness; a 55-year-old woman experienced an initial recovery from GBS after immunoglobulin treatment but relapsed shortly after due to treatment-related fluctuation (TRF).
- TRF involves temporary improvement followed by a setback in GBS symptoms within two months of the illness beginning, which happened in this case despite excluding other potential diagnoses like recurrent GBS.
- Factors such as other health issues, significant muscle weakness, and a lack of prior diarrhea indicated a higher risk for TRF, in addition to the role of early treatment and ongoing immune responses affecting recovery.