Photochemistry of UV-excited trifluoroacetylacetone and hexafluoroacetylacetone I: infrared spectra of fluorinated methylfuranones formed by HF photoelimination.

The photochemistry of gas-phase 1,1,1-trifluoroacetylacetone (TFAA) excited with ultraviolet (UV) light involves a significant photoelimination channel that produces hydrogen fluoride and a fluorinated methylfuranone, 2,2-difluoro-5-methyl-3(2H)-furanone (2FMF). This pathway is remarkable because it is a gas-phase unimolecular reaction that forms a five-membered ring product. This report is the first of such a TFAA photoelimination channel, which is similar to one observed with 1,1,1,5,5,5-hexafluoroacetylacetone (HFAA), resulting in 2,2-difluoro-5-trifluoromethyl-3(2H)-furanone.

Strategic approach for improving the medication-use process in health systems: the high-performance pharmacy practice framework.

Purpose: A strategic approach to improving the medication-use process in health systems by using a framework for setting priorities on the basis of feasibility, the potential for financial return, and the effect on quality and safety is described.

Summary: A panel consisting of leaders in health-system pharmacy identified seven dimensions of high-performance pharmacy (HPP) framework: medication preparation and delivery, patient care services, medication safety, medication-use policy, financial performance, human resources, and education. Performance elements, which are specific policies, procedures, activities, and practices that indicate high performance and result in a financial or clinical return on investment of resources, within each dimension were identified.