Publications by authors named "T Tharakan"
Chimeric Versus Multiple Simultaneous Free Flaps for Head and Neck Reconstruction.
Otolaryngol Head Neck Surg
December 2024
Objective: To describe our experience with chimeric flaps and to assess the surgical outcomes and postoperative complications associated with chimeric flaps compared to multiple flaps.
Study Design/methods: Patients undergoing chimeric and multiple simultaneous free tissue transfer between June 2016 and October 2023 were retrospectively reviewed. The primary outcome of interest was the complication rate.
Clinical studies in COVID-related olfactory disorders: Review of an institutional experience.
World J Otorhinolaryngol Head Neck Surg
June 2024
Objective: To share a single institutional experience with clinical research on COVID-related olfactory dysfunction (OD).
Data Source/method: Narrative review of published original data and ongoing clinical trials on COVID-related OD at Washington University from 2020 to 2023.
Results: There were three new diagnostic-/patient-reported outcome measures developed and tested.
Article Synopsis
- The study investigates whether using testicular sperm for ICSI is more effective than using ejaculated sperm in men with high sperm DNA fragmentation (SDF).
- Research included nine studies with over 536 participants, revealing that pregnancy and live birth rates were significantly higher with testicular sperm, while fertilisation and miscarriage rates showed no significant differences.
- The findings suggest potential benefits of testicular sperm, but the quality of evidence is limited, necessitating more rigorous research to confirm these results before changing clinical practices.
Context: Recommendations regarding the management of penile size abnormalities and dysmorphophobia are important in guiding evidence-based clinical practice.
Objective: To present a summary of the 2023 European Association of Urology sexual and reproductive health evidence-based recommendations for the management of penile size abnormalities and dysmorphophobia.
Evidence Acquisition: A broad and comprehensive scoping exercise covering all areas of the guidelines was performed.
Objectives: To compare taste changes after transoral robotic surgery (TORS) to taste changes in healthy controls.
Methods: Oropharyngeal cancer patients receiving TORS and healthy controls were recruited. Participants underwent posterolateral and whole-mouth psychophysical taste testing (identification, intensity, and hedonics) at baseline and at 2 weeks postoperatively (patients) or follow-up (controls).