Publications by authors named "T Tengs"

Atlantic cod farming experiences renewed growth in Norway, and increased awareness is essential to address emerging diseases in this species. There are few reports on gill diseases in cod, and to date, no viral gill infections of cod have been documented. In this study, we collected samples from three sequential time points in summer 2023 from farmed cod suffering from cardiorespiratory disease.

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Cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) has emerged with the rise of the aquaculture of Atlantic salmon (). The lack of cell culture cultivation has hampered the study of this infection. In this study, samples from naturally PMCV-infected Atlantic salmon from different commercial farms were collected and used.

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Spatial transcriptomics is a technique that provides insight into gene expression profiles in tissue sections while retaining structural information. We have employed this method to study the pathological conditions related to red and melanized focal changes in farmed Atlantic salmon (Salmo salar). Our findings support a model where similar molecular mechanisms are involved in both red and melanized filet discolorations and genes associated with several relevant pathways show distinct expression patterns in both sample types.

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Article Synopsis
  • - This study presents the first spatial transcriptomic atlas of Atlantic salmon skin using the Visium Spatial Gene Expression protocol, analyzing samples from four different skin areas of two fish.
  • - High-quality tissue sections were created, resulting in over 80 million reads per sample and the detection of more than 80,000 transcripts and nearly 30,000 genes, with epithelial tissues showing the highest transcript counts.
  • - Key findings include the identification of collagen type 1 as the most abundant gene family, along with specific gene markers for different tissue types, which were validated by a meta-analysis of existing microarray data.
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