Publications by authors named "T Tegos"
Article Synopsis
- A study was conducted to investigate the X-chromosome's role in Alzheimer's Disease (AD), which had been overlooked in previous genome-wide association studies.
- The research included 115,841 AD cases and 613,671 controls, considering different X-chromosome inactivation (XCI) states in females.
- While no strong genetic risk factors for AD were found on the X-chromosome, seven significant loci were identified, suggesting areas for future research.
Article Synopsis
- Hyperglycemia following a stroke can worsen the condition, so effective glucose management is crucial for reducing complications and improving patient outcomes.
- The study monitored 105 acute stroke patients’ glucose levels continuously over 72 hours, identifying various hyperglycemic patterns primarily occurring during night and morning hours.
- Findings suggest that traditional glucose tests may miss these patterns, highlighting the need for more frequent nighttime measurements and suggesting that admission glucose levels could help predict future hyperglycemic tendencies.
Article Synopsis
- The Oxfordshire Community Stroke Project categorizes ischemic strokes into four types and links hyperglycemia to larger infarct sizes and poorer patient outcomes.
- The study aimed to explore the relationship between glucose fluctuations and stroke types/outcomes using continuous glucose monitoring over 72 hours among recent stroke patients.
- Results indicated that while stroke subtype did not significantly affect mean glucose levels, improving glucose regulation could reduce the odds of poor outcomes, suggesting that strict glucose management might be more effective than focusing on stroke types.
Background: In recent years, studies have examined the acceptability and attitudes that influence the intention to early screen for Alzheimer's disease (AD) in the general population, older people, carers, and asymptomatic individuals who report a family history of AD. However, it remains unclear what specific factors promote or reduce the acceptability of pre-symptomatic screening.
Objective: The aim of this study is to explore the attitudes of family and non-family members as well as caregivers and non-caregivers toward the pre-symptomatic screening of AD.
Background: Pre-symptomatic screening methods for detecting a higher risk of Alzheimer's disease (AD) are gaining popularity; thus, more people are seeking these tests. However, to date, not much is known about the attitudes toward pre-symptomatic AD screening.
Objective: The goal of this study is to examine the psychometric properties of a tool for assessing the attitudes, barriers, and motivations to pre-symptomatic AD screening.