Background: This study aimed to explore the relationship between ultra-processed foods (UPFs) consumption and gut microbiota in patients with type 2 diabetes (T2D).
Methods: This cross-sectional study included 362 participants with T2D. UPFs consumption was assessed using a brief-type self-administered diet history questionnaire, quantified as the density of UPFs intake (g/1000 kcal).
Magenstrasse (stomach road) is reported to potentially influence the absorption of orally administered drugs by facilitating a gastric emptying of ingested water under postprandial condition. We hypothesized the Magenstrasse is a consequence of the formation of protein aggregates due to the decrease in gastric pH associated with stimulated gastric acid secretion. The formation mechanism of the Magenstrasse was examined in vitro using a gastric chamber system which reproduces postprandial conditions in the stomach.
View Article and Find Full Text PDFThree-dimensional (3D) and two-dimensional (2D) perovskite hybrid systems, known for their exceptional optoelectronic properties and stability, are revolutionizing optoelectronic materials research. However, fundamental physics of the 3D/2D interfaces and their dynamics remain poorly understood. We use fluorescence microspectroscopy to study the photoluminescence (PL) properties of 3D/2D nano-heterostructures of CsPbBr/PEAPbBr formed by postgrowth self-assembly.
View Article and Find Full Text PDFClasped thumb is characterised by thumb adduction and flexion deformity at the metacarpophalangeal joint caused by abnormalities in the extensor tendons. While conservative treatments are effective in infants, surgical intervention is necessary for older who experience deformities or functional impairments. We report an adolescent patient with an untreated clasped thumb who underwent extensor pollicis brevis (EPB) reconstruction using the extensor indicis proprius (EIP) tendon through the first dorsal compartment.
View Article and Find Full Text PDFObjective: Loss-of-function mutations in the GIRDIN/CCDC88A gene cause developmental epileptic encephalopathy (DEE) in humans. However, its pathogenesis is largely unknown. Global knockout mice of the corresponding orthologous gene (gKOs) have a preweaning lethal phenotype with growth failure, preventing longitudinal analysis.
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