The Role of Reduced Glutathione on the Activity of Adenosine Deaminase, Antioxidative System, and Aluminum and Zinc Levels in Experimental Aluminum Toxicity.

Aluminum (Al) is one of the most abundant element in the world. But aluminum exposure and accumulation causes serious diseases, related with free radicals. Reduced glutathione (GSH) is a tripeptide with intracellular antioxidant effects.

[Release of iron ions from transferrin under the effect of nitric oxide].

The dynamics of EPR signals from the iron-transporting blood protein Fe(3+)-transferrine after the administration of sodium nitrite and metronidazole to animals was studied. It was shown that exogenin nitric oxide produced by nitrocompounds resulted in the release of iron from Fe(3+)-transferrine.

[Effect of ascorbic acid on production of nitric oxide by leukocytes].

The effect of ascorbic acid on suspensions of blood formic elements was studied by the ESR method. It was shown that incubation of a suspension of formic blood elements in the presence of ascorbic acid leads to the appearance of nitric oxide, which is produced by leukocytes and partially probably by thrombocytes. The formation of nitric oxide is evidenced by the appearance of nitrosyl complexes heme-NO.