New Shikimic Acid Derivatives From the Marine-Derived Actinomycete Streptomyces sp. G666 and Their Antimicrobial Activities.

Analysis of an antimicrobial extract from the agar-based culture of the marine-derived actinomycete Streptomyces sp. G666 led to the isolation of three new shikimic acid derivatives, streptomine A-C (1-3), along with five known compounds (4-8). Their structures were established by their spectral data analyses, including MS and NMR.

Characteristics of Pseudomonas aeruginosa keratitis at Ho Chi Minh eye hospital.

Background: The increasing drug resistance of Pseudomonas aeruginosa (PA) poses a serious challenge to the current treatment. Antibiograms of this pathogen often take 3-5 days, and treatment of Pseudomonas aeruginosa keratitis (PAK) is mainly based on preliminary physical examination, clinical experience, and medical guidelines. Pertinent clinical data on the causative agent and antibiotics for high efficacy are essential for early recognition and subsequent treatment.

Evaluating the efficacy of intra-articular polydioxanone (PDO) injections as a novel viscosupplement in osteoarthritis treatment.

Aims: Osteoarthritis (OA) is a chronic joint disorder marked by cartilage breakdown, bone alterations, and inflammation, leading to significant pain and disability. Current therapeutic strategies, ranging from lifestyle interventions to pharmacological and surgical treatments, offer limited efficacy and are often accompanied by side effects. This study investigates the potential of Polydioxanone (PDO), a biocompatible synthetic polymer, as a novel intra-articular (IA) viscosupplement in OA.

Thermal Conductivity in Side-Chain Liquid-Crystal Epoxy Polymers: Influence of Mesogen Structure.

Side-chain liquid-crystal epoxy polymers (SCLCEPs) are valued for their unique properties, which combine LC side chains with epoxide-based polyether main chains for ordered molecular arrangements. They have high thermal conductivity and optical properties due to their low polydispersity and high crystallinity. Achieving optimal thermal conductivity in SCLCEPs involves addressing factors such as mesogen nature, polymer design, and alignment within the polymer structure.

Sequential Energy and Electron Transfer in Metal-Organic Frameworks.

This study presents the design and characterization of a triad metal-organic framework (MOF) system composed of pyrene, porphyrin, and phenyl-C-butyric acid (PCBA) for efficient energy and electron transfer processes mimicking natural photosynthesis. The triad MOF, synthesized through a mixed-ligand approach followed by postsynthetic modification, demonstrates sequential energy transfer from pyrene to porphyrin, followed by electron transfer to the PCBA acceptor. Time-resolved photoluminescence (TRPL) spectroscopy was employed to investigate the dynamics of energy and charge transfer, revealing fast interligand energy transfer and subsequent charge separation in the MOF structure.