Publications by authors named "T T Tidwell"
Objective: The virtual nurse (VN) pilot was developed to assist bedside nurses in administrative tasks, including discharges and education, from a remote location.
Background: Bedside nurse vacancies have increased, leading to a shortage of resources for the care team and less time for nurses to provide hands-on care to patients.
Methods: A survey showed 77% of nurses spend more than 3 hours per shift on admissions, discharges, and patient education.
Article Synopsis
- Hypobaric hypoxia, which causes altitude sickness, significantly affects human health, but studies on its proteomic and metabolic impacts in animals are limited.
- This study exposed male Sprague-Dawley rats to long-term (40 days) and short-term (3 days) hypoxia, comparing them with a normal control group, revealing notable changes in lipid metabolism markers.
- Key findings include increased levels of LDL, triglycerides, and total cholesterol in the liver, with distinct responses in HDL levels between long-term and short-term hypoxia, indicating significant biochemical changes due to varying exposure times.
To determine whether there is a correlation of genetic diagnosis/result with long-term seizure freedom in pediatric epilepsy patients. This was a prospective and retrospective cohort study of children with epilepsy referred for genetic testing at a single center. The primary outcomes were presence and type of genetic diagnosis (pathogenic, benign, or variant of uncertain significance) and patient epilepsy status (seizure free, treatment failure, uncertain).
View Article and Find Full Text PDFBackground: In vitro drug screening that is more translatable to the in vivo tumor environment can reduce both time and cost of cancer drug development. Here we address some of the shortcomings in screening and show how treatment with 5-fluorouracil (5-FU) in 2D and 3D culture models of colorectal cancer (CRC) and pancreatic ductal adenocarcinomas (PDAC) give different responses regarding growth inhibition.
Methods: The sensitivity of the cell lines at clinically relevant 5-FU concentrations was monitored over 4 days of treatment in both 2D and 3D cultures for CRC (SW948 and HCT116) and PDAC (Panc-1 and MIA-Pa-Ca-2) cell lines.
Article Synopsis
- Nonfatal firearm injuries account for 68% of firearm-related injuries, leading to significant health and financial impacts on patients and the healthcare system.
- A study analyzed 359 adults in the Southeastern U.S. from 2019 to 2021, revealing an average total cost of stay of $36,639.12 and an average length of stay of 8.61 days.
- The study found that vascular and traumatic brain injuries contributed to higher costs and longer hospital stays, while bony injuries resulted in more follow-up appointments, informing trauma protocols to potentially reduce financial burdens.