Effect of folpet on hypoglycaemia, intestinal microbiota, and drug resistance genes in mice.

Background: Folpet is a nonspecific sulfonamide fungicide widely used to protect crops from mildew. However, the in vivo effects of folpet on glucose metabolism homeostasis, gut microbiota, and abundance of drug resistance genes remain unknown. The purpose of this study was to assess the effects of the pesticide, folpet, on glucose metabolism homeostasis, and folpet-induced changes in the intestinal microbiota and resistance genes in mice.

Poly(lactide)/poly(butylene adipate-co-terephthalate)/carbon nanotubes composites with robust mechanical properties, fatigue-resistance and dielectric properties.

A styrene-glycidylmethacrylate-1-allyl-3-vinylimidazole epoxy functionalized ionomer (EFI) was synthesized, and the EFI and carbon nanotubes (CNTs) were co-introduced into poly(lactide)/poly(butylene-adipate-co-terephtalate) (PLA/PBAT) blends to fabricate high performance composites with excellent mechanical properties, fatigue-resistance and dielectric properties. It is revealed that EFI can improve the interaction force between PLA and PBAT by inducing the interfacial crosslink reaction, thereby improving the melt strength of the samples. EFI can also refine the dispersion of CNT in the composites owing to the non-covalent force between EFI and CNT, promote the formation of filler network inside composites, which is demonstrated by DMA and rheological test results.

A Cerium Oxide Loaded Hyaluronic Acid Nanosystem Remits Glucose Oxidative Stress-Induced Odontoblasts Mitochondrial Apoptosis through Regulation of PGAM5 Pathway.

Diabetes mellitus (DM) induced mitochondrial oxidative stress (OS) can lead to severe injury of dental pulp. The cerium oxide nanoparticles (CNP) have been proven to have excellent antioxidative activity. However, whether CNP can relieve dental pulp damage caused by DM and the underlying mechanisms remain unclear.

High prevalence and plasmidome diversity of -positive enterococci in a Shenzhen community, China.

Background: The emergence of , which can confer resistance to phenicols and oxazolidinones in spp., poses a growing public health threat.

Methods: 102 -positive enterococci (OPEs) including various species were isolated from feces of 719 healthy volunteers in a Shenzhen community, China.

A Comprehensive Evaluation of Goslings-II: A Sustainable Early Language and Literacy Program for NICU Parents.

This program evaluation aimed to assess the impact of a streamlined and less expensive version of Goslings-I (a NICU parent education program) on parents' early language and literacy practices and their confidence in interacting with their infants. This evaluation used a single-group, pre- and posttest, mixed-methods design. Sixty-three parents completed pre- and postprogram questionnaires on the frequency of language and literacy activities, confidence in understanding infant signals, and program satisfaction.