Irreversible Electroporation and β-Glucan Induced Trained Innate Immunity for the Treatment of Pancreatic Ductal Adenocarcinoma: A Phase II Study.

Introduction: Irreversible electroporation(IRE) has augmented the effects of certain immunotherapies in pancreatic cancer(PDA). Yeast-derived particulate beta-glucan induces trained innate immunity and has successfully reduces murine PC tumor burden. This is a Phase II study to test the hypothesis that IRE may augment beta-glucan induced trained immunity in patients with PDA.

Significance of finite difference approach for application of Cattaneo-Christov theory conveying radiative ternary-hybrid nanofluids flow.

This paper investigates the characteristics of ternary-hybrid nanoliquid for time-dependent Darcy-Forchheimer flow. Formulation is based for mixture of water subject to ternary nanoparticles with different shapes like (platelet, spherical and cylindrical). Heat transfer consists of convective condition, radiation and heat generation.

Preoperative liquid biopsy for optimal patient selection in metastatic colorectal cancer.

Objective: In this pilot study, we sought to determine if preoperative circulating tumor DNA could be a useful predictor to avoid futile metastasectomy, predict early postoperative recurrence, and determine optimal chemotherapy duration during the management of patients with resectable metastatic colorectal cancer.

Methods: Patients from 2021 to 2023 were enrolled prospectively and evaluated with circulating tumor DNA preoperatively and postoperatively for detection of recurrence. Clinicopathologic and treatment factors as well as disease-free survival were compared between those with undetectable versus detectable preoperative circulating tumor DNA.

Creative webs: decoding the creativity potential of Twitter followers.

Introduction: Previous studies have associated creativity to one's social networks. This study builds on this framework and examines the premise that one's social fabric is a catalyst for creativity, specifically probing the dynamics between online social connections and creative expressions in the realm of Esports. Therefore, this research paper examined a correlation between people's creativity and their Effective Network Size (non-redundant ties) on Twitter, to see if potentially non-redundant information is related to creativity.