Nanoparticles Targeted to Fibroblast Activation Protein Outperform PSMA for MRI Delineation of Primary Prostate Tumors.

Accurate delineation of gross tumor volumes remains a barrier to radiotherapy dose escalation and boost dosing in the treatment of solid tumors, such as prostate cancer. Magnetic resonance imaging (MRI) of tumor targets has the power to enable focal dose boosting, particularly when combined with technological advances such as MRI-linear accelerator. Fibroblast activation protein (FAP) is overexpressed in stromal components of >90% of epithelial carcinomas.

Characterisation of internal oxygen concentration of strawberry ( × ) and blueberry ().

Gas exchange mechanisms play crucial roles in maintaining fruit post-harvest quality in perishable fruit such as strawberry (Fragaria×ananassa Duch.) and blueberry (Vaccinium corymbosum L.).

MRI Detection of Hepatic -Acetylcysteine Uptake in Mice.

This proof-of-concept study looked at the feasibility of using a thiol-water proton exchange (i.e., CEST) MRI contrast to detect in vivo hepatic -acetylcysteine (NAC) uptake.

Preferential freezing avoidance localised in anthers and embryo sacs in wintering Daphne kamtschatica var. jezoensis flower buds visualised by magnetic resonance imaging.

To explore diversity in cold hardiness mechanisms, high resolution magnetic resonance imaging (MRI) was used to visualise freezing behaviours in wintering Daphne kamtschatica var. jezoensis flower buds, which have naked florets and no bud scales. MRI images showed that anthers remained stably supercooled to the range from -14 to -21°C or lower while most other tissues froze by -7°C.

Explicit phenomenological solutions for magnetization exposed to an arbitrary NMR diffusion steady state pulse sequence.

Explicit phenomenological solutions to recurrence relations for the bulk transverse and longitudinal magnetization found using the Torrey-Bloch equations with relaxation effects are used to investigate nuclear magnetic resonance (NMR) diffusion measurements. Of particular interest are steady state NMR (self-)diffusion measurements that reduce experimental time that can extend the techniques to quickly reacting systems. The solutions for bulk transverse and longitudinal magnetization presented here are used to investigate the average behavior of the transverse and longitudinal magnetization in forming a steady state and are used to derive new expressions for the steady state longitudinal magnetization.